I've only done so in training...drawing from a holster while releasing the seat belt in those tight quarters can be awkward unless a system is practiced and employed in the correct order while keeping your vision locked on the threat.
Helpful video. I especially liked (1) better to drive away, when possible, than shoot from a car, (2) use steering wheel to shape the arc of weapon presentation, and especially the "pro tip" (3) practice this in your garage rather than driveway so that your neighbors don't call the police! Question: Any suggestions for lefties?